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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP5
All Species:
33.33
Human Site:
S581
Identified Species:
52.38
UniProt:
Q8N3R9
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3R9
NP_071919.2
675
77294
S581
L
L
S
L
R
T
Q
S
L
K
T
L
R
N
S
Chimpanzee
Pan troglodytes
XP_510014
764
85553
S670
L
L
S
L
R
T
Q
S
L
K
T
L
R
N
S
Rhesus Macaque
Macaca mulatta
XP_001105724
674
77301
S580
L
L
S
L
R
T
Q
S
L
K
T
L
R
N
S
Dog
Lupus familis
XP_547862
675
77214
S581
L
L
S
L
R
T
Q
S
L
K
T
L
R
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLB2
675
77211
S581
L
L
S
L
R
T
Q
S
L
K
T
L
R
N
S
Rat
Rattus norvegicus
Q5U2Y3
576
65604
E492
F
I
K
P
P
S
I
E
R
L
R
E
T
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505475
675
76860
S581
L
L
N
L
H
T
Q
S
L
K
S
L
R
N
S
Chicken
Gallus gallus
Q5ZJ00
468
52501
L387
L
D
I
E
P
Q
T
L
K
I
V
R
T
A
E
Frog
Xenopus laevis
NP_001085267
675
76810
S581
L
L
C
L
H
T
Q
S
L
K
M
L
R
N
S
Zebra Danio
Brachydanio rerio
Q8JHF4
677
76390
S583
L
L
C
V
H
T
Q
S
L
K
V
L
R
S
S
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
M386
L
D
V
E
P
Q
T
M
K
V
L
R
T
A
D
Fruit Fly
Dros. melanogaster
Q24210
898
100893
A813
I
L
D
V
E
P
Q
A
L
K
I
L
R
T
A
Honey Bee
Apis mellifera
XP_393395
1033
115664
S939
V
L
N
L
H
P
Q
S
L
K
I
L
R
N
S
Nematode Worm
Caenorhab. elegans
P54936
961
108794
A876
I
L
D
V
E
P
Q
A
L
K
V
L
R
T
A
Sea Urchin
Strong. purpuratus
XP_784409
971
107892
A877
L
L
N
L
H
A
Q
A
L
K
I
L
K
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.6
97
98.2
N.A.
96.7
36.2
N.A.
93.7
25
86
77
25.7
26.7
34.7
24.1
34.7
Protein Similarity:
100
87.5
97.7
99.5
N.A.
98.6
54.9
N.A.
96.8
43.8
92.5
86.7
44.5
46.3
49.2
41.7
49.2
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
80
6.6
80
66.6
6.6
40
66.6
40
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
93.3
6.6
80
80
6.6
66.6
80
66.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
20
0
0
0
0
0
14
14
% A
% Cys:
0
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
14
14
0
0
0
0
0
0
0
0
0
0
0
7
% D
% Glu:
0
0
0
14
14
0
0
7
0
0
0
7
0
0
7
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
34
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
14
7
7
0
0
0
7
0
0
7
20
0
0
0
0
% I
% Lys:
0
0
7
0
0
0
0
0
14
80
0
0
7
7
7
% K
% Leu:
74
80
0
60
0
0
0
7
80
7
7
80
0
0
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
7
0
0
0
0
% M
% Asn:
0
0
20
0
0
0
0
0
0
0
0
0
0
54
0
% N
% Pro:
0
0
0
7
20
20
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
14
80
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
34
0
0
0
7
0
7
14
74
7
0
% R
% Ser:
0
0
34
0
0
7
0
60
0
0
7
0
0
7
67
% S
% Thr:
0
0
0
0
0
54
14
0
0
0
34
0
20
14
0
% T
% Val:
7
0
7
20
0
0
0
0
0
7
20
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _